LL 37

LL-37 (375 – 10MG) by GX Peptide Supply is a 37-amino acid, amphipathic alpha-helical peptide derived from the C-terminus of the human cathelicidin antimicrobial protein hCAP18. As a critical component of the human innate immune system, LL-37 is widely utilized in research to understand how the body provides a primary defense against various pathogens.

Key Research Properties:

• Broad-Spectrum Antimicrobial Activity: Extensively studied for its ability to directly disrupt the cell membranes of Gram-positive and Gram-negative bacteria, as well as certain fungi and viral envelopes.

• Immunomodulatory Signaling: Investigated for its role as a “chemokine,” recruiting immune cells like neutrophils and T-lymphocytes to sites of infection or injury.

• Wound Healing & Angiogenesis: Targeted in laboratory models examining the promotion of re-epithelialization and the development of new blood vessels during tissue repair.

• Neutralization of Endotoxins: Research focus includes its capacity to bind and neutralize Lipopolysaccharides (LPS), potentially mitigating excessive inflammatory responses.

Product Specifications:

• Product Code: 375.

• Concentration: 10mg per vial.

• Format: Lyophilized (freeze-dried) powder to ensure high stability and molecular integrity.

• Quality Standard: Manufactured by GX Peptide Supply to meet rigorous analytical standards for sequence accuracy and purity.

Storage & Handling Guidelines:

• Temperature: Store non-reconstituted vials at -20°C for optimal long-term shelf life.

• Light Protection: Housed in specialized light-resistant vials to safeguard the peptide from UV-induced degradation.

• Reconstitution: For best results, use sterile laboratory-grade solvents under aseptic conditions; avoid mechanical stress or vigorous agitation of the solution.